This randomized, double-blind trial finds that one-month of omega-3 fatty acid intake significantly reduces the signs and symptoms of dry eye. Subjects included 64 patients aged 45 to 90 years, 33 of which received two capsules of omega-3 fatty acids daily, while the remaining patients received two capsules of medium-chain triglyceride oil daily. At one month, tear break-up time improved 71 percent compared with 3.3 percent in the placebo group. Improvement also was observed in the secondary outcome measures, Ocular Surface Disease Index score and Schirmer's score.

Ophthalmology, November 2013